SBIO ETF

SBIO ETF
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CGON is SBIO's largest holding at 3.73% of the fund as of Oct 8, 2026. SBIO is ALPS Medical Breakthroughs ETF.

Showing top 50 of 104 holdings · as of Oct 8, 2026
SBIO holdings, by weight
#TickerNameWeightCumulativeSharesMkt valueSectorIndustry
1
CGON
Cg Oncology IncHealth Care · Biotechnology
3.73%		3.7%112,596$7.02MHealth CareBiotechnology
2
ORKA
Oruka Therapeutics Inc OrkaHealth Care · Biotechnology
3.55%		7.3%84,115$6.69MHealth CareBiotechnology
Sector and industry · Pro
3
TVTX
Travere Therapeutics Inc
3.40%		10.7%119,727$6.40M
4
DNTH
Dianthus Therapeutics Inc
3.20%		13.9%71,016$6.03M
5—Definium Therapeutics, Inc. Common Shares
3.18%		17.1%170,644$5.99M
6
MANE
Veradermics Inc
3.13%		20.2%53,064$5.89M
7
EWTX
Edgewise Therapeutics Inc.
2.90%		23.1%137,912$5.46M
8
RLAY
Relay Therapeutics Inc
2.65%		25.7%278,309$5.00M
9
XENE
Xenon Pharmaceuticals Inc. Common Shares
2.38%		28.1%122,979$4.48M
10
IDYA
Ideaya Biosciences Inc
2.36%		30.5%122,543$4.44M
11
AMLX
Amylyx Pharmaceuticals Inc
2.32%		32.8%159,427$4.37M
12
ACAD
Acadia Pharmaceuticals Inc
2.28%		35.1%218,864$4.30M
13
TARS
Tarsus Pharmaceuticals Inc
2.18%		37.3%55,724$4.10M
14
DNLI
Denali Therapeutics Inc
2.07%		39.3%203,012$3.89M
15—Dynegy
2.01%		41.3%237,167$3.79M
16
ZLAB
Zai Lab Ltd
1.92%		43.3%142,831$3.62M
17
NAMS
Newamsterdam Pharma Company Nv
1.78%		45.0%151,846$3.36M
18
MBX
Mbx Biosciences Inc
1.77%		46.8%61,160$3.34M
19
CLDX
Celldex Therapeutics Inc
1.61%		48.4%99,752$3.04M
20
IRON
Disc Medicine, Inc.
1.58%		50.0%48,750$2.98M
21
SLS
Sellas Life Sciences Group Inc.
1.54%		51.5%256,475$2.90M
22
VERA
Vera Therapeutics Inc Ser C Pc Pp
1.47%		53.0%91,547$2.77M
23
IMNM
Immunome Inc
1.46%		54.5%144,280$2.76M
24
BCRX
BioCryst Pharmaceuticals Inc.
1.45%		55.9%324,541$2.73M
25
VCEL
Vericel Corp
1.41%		57.3%65,052$2.65M
26
VRDN
Viridian Therapeutics Ors Inc
1.40%		58.7%143,868$2.63M
27
LKFT
Lakefront Biotherapeutics Sponsored Adr (1 Ads : 1 Ordinary)
1.35%		60.1%84,605$2.54M
28
MLYS
Mineralys Therapeutics Inc
1.32%		61.4%112,297$2.48M
29
AGIO
Agios Pharmaceuticals Inc
1.28%		62.7%75,811$2.41M
30—Structure Therapeutics Inc Adr
1.28%		64.0%90,593$2.42M
31
PVLA
Palvella Therapeutics Inc
1.27%		65.2%18,307$2.39M
32
SRPT
Sarepta Therapeutics Inc
1.25%		66.5%134,154$2.35M
33
ZBIO
Zenas Biopharma Inc
1.24%		67.7%82,799$2.33M
34
XNCR
Xencor Inc
1.22%		68.9%94,438$2.29M
35
GENB
Generate Biomedicines Inc
1.18%		70.1%163,010$2.21M
36
NUVB
Nuvation Bio Inc
1.15%		71.3%445,937$2.17M
37
CMPS
Compass Pathways Plc Adr
1.09%		72.4%175,868$2.06M
38
STOK
Stoke Therapeutics Inc
1.06%		73.4%81,949$1.99M
39—Immunocore Holdings Plc American Depositary Shares, Each Representing One Ordinary Share, Nominal Value ‚0.002 Per Share
1.02%		74.4%65,426$1.92M
40
RAPP
Rapport Therapeutics, Inc.
1.00%		75.4%60,937$1.88M
41
MAZE
Maze Therapeutics Inc
0.98%		76.4%70,532$1.85M
42
TSHA
Taysha Gene Therapies Inc
0.97%		77.4%413,813$1.83M
43
NKTR
Nektar Therapeutics
0.93%		78.3%43,387$1.75M
44
KLRA
Kailera Therapeutics Inc
0.92%		79.2%164,635$1.73M
45
TYRA
Tyra Biosciences Inc
0.82%		80.1%75,781$1.55M
46
MNKD
Mannkind Corporation Com New
0.75%		80.8%408,398$1.41M
47
VOR
Vor Biopharma Inc.
0.75%		81.6%75,131$1.41M
48
IMTX
Immatics N.V. Ordinary Shares
0.75%		82.3%190,037$1.42M
49
LBRX
Lb Pharmaceuticals Inc.
0.74%		83.0%40,962$1.40M
50
BCAX
Bicara Therapeutics, Inc.
0.73%		83.8%84,068$1.38M
More holdings · Pro
Not reported for this fund: share changes.
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SBIO ETF All Holdings

SBIO holdings total 105 positions. The top 10 holdings account for 30.5% of the fund, led by Cg Oncology Inc at 3.7%, Oruka Therapeutics Inc Orka at 3.5%, Travere Therapeutics Inc at 3.4%.

SBIO portfolio concentration is moderate, with the top 10 representing 30.5% of total assets. The largest sector exposure is Health Care at 86.7%.

SBIO sectors provide a detailed breakdown. SBIO overlap shows how holdings compare to other funds in your portfolio.

Compare SBIO

SBIO vs SPYSBIO vs QQQSBIO vs VOOSBIO vs VTISBIO vs IVVSBIO vs SCHDSBIO vs VYMSBIO vs VXUS

SBIO ETF Holdings

104 of 105 holdings

  • 1

    Cg Oncology Inc

    CGONHealth Care
    3.73%
  • 2

    Oruka Therapeutics Inc Orka

    ORKAHealth Care
    3.55%
  • 3

    Travere Therapeutics Inc

    TVTXHealth Care
    3.40%
  • 4

    Dianthus Therapeutics Inc

    DNTHHealth Care
    3.20%
  • 5

    Definium Therapeutics, Inc. Common Shares

    DFTX:CAUnknown
    3.18%
  • 6

    Veradermics Inc

    MANEUnknown
    3.13%
  • 7

    Edgewise Therapeutics Inc.

    EWTXHealth Care
    2.90%
  • 8

    Relay Therapeutics Inc

    RLAYHealth Care
    2.65%
  • 9

    Xenon Pharmaceuticals Inc. Common Shares

    XENEHealth Care
    2.38%
  • 10

    Ideaya Biosciences Inc

    IDYAHealth Care
    2.36%
  • 11

    Amylyx Pharmaceuticals Inc

    AMLXHealth Care
    2.32%
  • 12

    Acadia Pharmaceuticals Inc

    ACADHealth Care
    2.28%
  • 13

    Tarsus Pharmaceuticals Inc

    TARSHealth Care
    2.18%
  • 14

    Denali Therapeutics Inc

    DNLIHealth Care
    2.07%
  • 15

    Dynegy

    DYNHealth Care
    2.01%
  • 16

    Zai Lab Ltd

    ZLABHealth Care
    1.92%
  • 17

    Newamsterdam Pharma Company Nv

    NAMSHealth Care
    1.78%
  • 18

    Mbx Biosciences Inc

    MBXHealth Care
    1.77%
  • 19

    Celldex Therapeutics Inc

    CLDXHealth Care
    1.61%
  • 20

    Disc Medicine, Inc.

    IRONHealth Care
    1.58%
  • 21

    Sellas Life Sciences Group Inc.

    SLSHealth Care
    1.54%
  • 22

    Vera Therapeutics Inc Ser C Pc Pp

    VERAHealth Care
    1.47%
  • 23

    Immunome Inc

    IMNMHealth Care
    1.46%
  • 24

    BioCryst Pharmaceuticals Inc.

    BCRXHealth Care
    1.45%
  • 25

    Vericel Corp

    VCELHealth Care
    1.41%
  • 26

    Viridian Therapeutics Ors Inc

    VRDNHealth Care
    1.40%
  • 27

    Lakefront Biotherapeutics Sponsored Adr (1 Ads : 1 Ordinary)

    GLPG:BRHealth Care
    1.35%
  • 28

    Mineralys Therapeutics Inc

    MLYSHealth Care
    1.32%
  • 29

    Agios Pharmaceuticals Inc

    AGIOHealth Care
    1.28%
  • 30

    Structure Therapeutics Inc Adr

    GPCR:SHHealth Care
    1.28%
  • 31

    Palvella Therapeutics Inc

    PVLAHealth Care
    1.27%
  • 32

    Sarepta Therapeutics Inc

    SRPTHealth Care
    1.25%
  • 33

    Zenas Biopharma Inc

    ZBIOHealth Care
    1.24%
  • 34

    Xencor Inc

    XNCRHealth Care
    1.22%
  • 35

    Generate Biomedicines Inc

    GENBUnknown
    1.18%
  • 36

    Nuvation Bio Inc

    NUVBHealth Care
    1.15%
  • 37

    Compass Pathways Plc Adr

    CMPSHealth Care
    1.09%
  • 38

    Stoke Therapeutics Inc Com

    STOKHealth Care
    1.06%
  • 39

    Immunocore Holdings Plc American Depositary Shares, Each Representing One Ordinary Share, Nominal Value ‚0.002 Per Share

    IMCR:LNHealth Care
    1.02%
  • 40

    Rapport Therapeutics, Inc.

    RAPPHealth Care
    1.00%
  • 41

    Maze Therapeutics Inc

    MAZEHealth Care
    0.98%
  • 42

    Taysha Gene Therapies Inc

    TSHAHealth Care
    0.97%
  • 43

    Nektar Therapeutics Common Stock Usd.0001

    NKTRHealth Care
    0.93%
  • 44

    Kailera Therapeutics Inc

    KLRAUnknown
    0.92%
  • 45

    Tyra Biosciences Inc

    TYRAHealth Care
    0.82%
  • 46

    Mannkind Corporation Com New

    MNKDHealth Care
    0.75%
  • 47

    Vor Biopharma Inc.

    VORUnknown
    0.75%
  • 48

    Immatics N.V. Ordinary Shares

    4A3:BEHealth Care
    0.75%
  • 49

    Lb Pharmaceuticals Inc.

    LBRXUnknown
    0.74%
  • 50

    Bicara Therapeutics, Inc.

    BCAXHealth Care
    0.73%
  • 51

    Meiragtx Holdings Plc Ordinary Shares

    MGTX:KYHealth Care
    0.70%
  • 52

    Seaport Therapeutics Inc

    SPTXUnknown
    0.65%
  • 53

    Kura Oncology Inc

    KURAHealth Care
    0.64%
  • 54

    Alto Neuroscience, Inc., Series C

    ANROHealth Care
    0.62%
  • 55

    Rigel Pharmaceuticals Inc

    RIGLHealth Care
    0.60%
  • 56

    Corvus Pharmaceuticals Inc

    CRVSHealth Care
    0.59%
  • 57

    ARRIVENT BIOPHARMA INC

    AVBPHealth Care
    0.56%
  • 58

    Spyglass Pharma Inc

    SGPUnknown
    0.54%
  • 59

    Geron Corp

    GERNHealth Care
    0.52%
  • 60

    Candel Therapeutics Inc.

    CADLHealth Care
    0.51%
  • 61

    Solid Biosciences Inc

    SLDBHealth Care
    0.50%
  • 62

    Design Therapeutics Inc.

    DSGNHealth Care
    0.49%
  • 63

    4d Molecular Therapeutics Inc.

    FDMTHealth Care
    0.47%
  • 64

    Olema Pharmaceuticals Inc

    OLMAHealth Care
    0.47%
  • 65

    Wave Life Sciences Ltd

    WVEHealth Care
    0.47%
  • 66

    Climb Bio Inc

    CLYMHealth Care
    0.42%
  • 67

    Fulgent Genetics Inc

    FLGTHealth Care
    0.38%
  • 68

    Delcath Systems Inc

    DCTHHealth Care
    0.36%
  • 69

    Altimmune Inc

    ALTHealth Care
    0.35%
  • 70

    NEURogene

    NGNEUnknown
    0.35%
  • 71

    Oculis Holding Ag Ordinary Shares

    OCS:SMUnknown
    0.35%
  • 72

    Aclaris Therapeutics Inc

    ACRSHealth Care
    0.34%
  • 73

    Allogene Therapeutics Inc

    ALLOHealth Care
    0.33%
  • 74

    Tectonic Therapeutic Inc Pipe

    TECXHealth Care
    0.30%
  • 75

    AgomAb Therapeutics NV Each ADS represents one common share

    AGMB:BRUnknown
    0.29%
  • 76

    Contineum Therapeutics Inc-A

    CTNMHealth Care
    0.28%
  • 77

    Rezolute Inc Pipe Deal Rzlt

    RZLTHealth Care
    0.28%
  • 78

    Eikon Therapeutics Inc

    EIKNUnknown
    0.27%
  • 79

    ZURA BIO LTD COMMON STOCK

    ZURA:KYUnknown
    0.27%
  • 80

    Enanta Pharmaceuticals Inc

    ENTAHealth Care
    0.24%
  • 81

    Arcturus Therapeutics Holdings Inc.

    ARCTUnknown
    0.24%
  • 82

    C4 Therapeutics Inc Ordinary Shares

    CCCCHealth Care
    0.23%
  • 83

    Relmada Therapeutics Inc Common Stock

    RLMDHealth Care
    0.23%
  • 84

    Fulcrum Therapeutics Inc Com

    FULCHealth Care
    0.19%
  • 85

    X4 Pharmaceuticals, Inc.

    XFORHealth Care
    0.19%
  • 86

    Inhibikase Thera

    IKTHealth Care
    0.18%
  • 87

    Sab Biotherapeutics, Inc.

    SABSHealth Care
    0.18%
  • 88

    Immuneering Corp.

    IMRXHealth Care
    0.17%
  • 89

    Upstream Bio Inc

    UPBHealth Care
    0.17%
  • 90

    Akebia Therapeutics Inc

    AKBAHealth Care
    0.16%
  • 91

    Evommune Inc

    EVMNUnknown
    0.15%
  • 92

    Macrogenics Inc

    MGNXHealth Care
    0.15%
  • 93

    Sionna Therapeutics Inc

    SIONHealth Care
    0.15%
  • 94

    Bicycle Therapeutics Plc-Adr

    BCYC:LNHealth Care
    0.13%
  • 95

    COMPASS THERAPEUTICS INC

    CMPXHealth Care
    0.12%
  • 96

    I Mab

    IMABUnknown
    0.10%
  • 97

    Protara Therapeutics Inc

    TARAHealth Care
    0.10%
  • 98

    Anavex Life Scienc Com New

    AVXLHealth Care
    0.09%
  • 99

    Immunic Inc.

    IMUXUnknown
    0.07%
  • 100

    Tenax Therapeutics Inc

    TENXUnknown
    0.05%
  • 101

    Cash Equivalent

    Other
    0.03%
  • 102

    Contra Chinook Therape

    KDNYUnknown
    0.00%
  • 103

    Astrazeneca Plc

    AZN:LNUnknown
    0.00%
  • 104

    Novo Nordisk Class B

    NOVOB:COUnknown
    0.00%